Alveolar rhabdomyosarcoma of maxilla

Nasal Alveolar Rhabdomyosarcoma

Rhabdomyosarcoma is a soft tissue sarcoma arising from cells of myogenic lineage. They can be divided into Embryonal rhabdomyosarcoma (ERMS), Alveolar rhabdomyosarcoma (ARMS) and Pleomorphic rhabdomyosarcoma. ARMS occurs in 10-25years age group and the most common sites being extremities, perirectal and perineal regions, head and neck region is frequently involved in childhood but is exceedingl...

Pancreatic Metastasis of Alveolar Rhabdomyosarcoma Presenting as Acute Pancreatitis

Alveolar Rhabdomyosarcoma Involving the Heart

A 12-year-old girl, who had had an above-knee amputation of the left leg for a soft tissue sarcoma six years prior to this admission, presented with syncope, angina, and signs of aortic stenosis. Echocardiography demonstrated a mass arising from the interventricular septum with obstruction of the left ventricular outflow tract and aortic valve. Cardiac catheterization and angiography con-

NFκB signaling in alveolar rhabdomyosarcoma

Alveolar rhabdomyosarcoma (aRMS) is a pediatric soft tissue cancer commonly associated with a chromosomal translocation that leads to the expression of a Pax3:Foxo1 or Pax7:Foxo1 fusion protein, the developmental underpinnings of which may give clues to its therapeutic approaches. In aRMS, the NFκB-YY1-miR-29 regulatory circuit is dysregulated, resulting in repression of miR-29 and loss of the ...

Primary cerebral alveolar rhabdomyosarcoma in adult

Primary cerebral rhabdomyosarcomas are very rare and malignant tumors that occur predominantly in the posterior fossa of pediatric patients. We report a rare case of primary cerebral rhabdomyosarcoma located in the supratentorial compartment of a 51 year-old woman together with a review of the pertinent Literature especially regarding the histological diagnosis and pitfalls.